Life Learning Pathway
Systematic study of life sciences, tracking the latest research progress, applied to personal health management
Core Learning Areas
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Cellular Aging Mechanisms
Understanding the molecular mechanisms of cellular aging, including telomere attrition, epigenetic changes, protein homeostasis imbalance, etc.
- Telomere and telomerase research
- Epigenetic clock
- Cellular senescence markers
- Senolytics (senescent cell clearance agents)
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Mitochondrial Function
Mitochondria are the cell's powerhouses, their functional decline is closely related to aging
- Mitochondrial biogenesis
- NAD+ supplements (NMN/NR)
- Mitophagy
- Oxidative stress management
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Metabolism and Health
Regulation of metabolic pathways is a key target for extending healthy lifespan
- mTOR signaling pathway
- AMPK activation
- Insulin sensitivity
- Intermittent fasting
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Supplements and Interventions
Nutrition supplements and drug interventions based on scientific evidence
- Metformin
- Rapamycin
- Resveratrol
- Vitamin D3 + K2
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Biomarker Monitoring
Tracking aging process through blood tests and physiological indicators
- Inflammatory markers (CRP, IL-6)
- Hormone levels
- Blood lipids and glucose
- Epigenetic age testing
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AI+ Bioinformatics
Applications of artificial intelligence in life research
- Drug discovery acceleration
- Personalized medicine
- Aging prediction models
- Genomic data analysis
Learning Progress Tracking
Fundamental Theory of Cellular Aging
In Progress 60%Mitochondrial Function and NAD+
In Progress 45%Metabolic Pathways and mTOR
Not Started 0%Scientific Evaluation of Supplements
Not Started 0%Recommended Readings and Research
π Core Books
- "Lifespan" - David Sinclair (Harvard Genetics Professor)
- "Outlive" - Peter Attia (Biomedical Expert)
- "The Longevity Paradox" - Steven Gundry
- "Young Forever" - Mark Hyman
π Key Papers and Resources
- "Hallmarks of Aging" - Cell, 2013/2023 updated version
- David Sinclair lab research (harvard.edu)
- Buck Institute for Research on Aging
- AFAR (American Federation for Aging Research)
π§ Podcasts and Interviews
- The Peter Attia Drive
- FoundMyFitness (Rhonda Patrick)
- Huberman Lab
- David Sinclair interview collection